Acne Treatment
Welcome to my blog post about Acne Treatment. Acne is a disease of pilosebaceous unit, characterized by accumulation of
sebum, overgrowth of Propionibacterium acnes and inflammation. This skin condition can be very bothersome and irritating to all
The anti-acne treatment should be initiated early in order to prevent the formation of scars.
The treatment requires a relatively long time. An improvement can be observed after about 2 months of therapy. Topical treatment is indicated in mild to moderate acne, whereas systemic in moderate to severe, however only women can be useful to use hormone therapy.
Topical antimicrobials
The comedones and inflammatory lesions respond well to benzoyl peroxide.
Benzoyl peroxide should be applied starting with low concentrations, and then increase it gradually.
The most common side effect was local skin irritation.
An alternative to Benzoyl peroxide is represented by the acid Azelaic.
If there is no improvement after 2 months of treatment with topical antimicrobials, may be appropriate to move on to treatment with topical antibiotics.
Antibiotics for topical use
The topical antibiotics (erythromycin, clindamycin) are effective in acne inflammation.
The main limitation in the use of topical antibiotics is the emergence of antibiotic resistance on the part of Propionibacterium acnes.
To avoid development of resistance:
- Avoid concomitant treatment with oral antibiotics
- Not to continue the antibiotic treatment longer than necessary
- Short treatment with antimicrobials (benzoyl peroxide, azelaic acid).
Topical retinoids
The tretinoin, isotretinoin and its isomer, are indicated for the treatment of comedonal acne. Treatment should be continued until no new lesions appear. Topical retinoids should not be used in acne severe, affecting a large body area.
These drugs should be used with caution on sensitive skin, avoiding contact with mucous membranes.
It should also be avoided exposure to UV light (sunlight, sunlamps).
Retinoids are contraindicated in pregnancy.
The most common side effects observed after treatment with topical retinoids are local reactions, such as burning, erythema, abrasions, itching, dryness, peeling. You can see temporary changes in skin pigmentation. The Adapalene is less irritating effects than other topical retinoids.
The anti-acne treatment should be initiated early in order to prevent the formation of scars.
The treatment requires a relatively long time. An improvement can be observed after about 2 months of therapy. Topical treatment is indicated in mild to moderate acne, whereas systemic in moderate to severe, however only women can be useful to use hormone therapy.
Topical antimicrobials
The comedones and inflammatory lesions respond well to benzoyl peroxide.
Benzoyl peroxide should be applied starting with low concentrations, and then increase it gradually.
The most common side effect was local skin irritation.
An alternative to Benzoyl peroxide is represented by the acid Azelaic.
If there is no improvement after 2 months of treatment with topical antimicrobials, may be appropriate to move on to treatment with topical antibiotics.
Antibiotics for topical use
The topical antibiotics (erythromycin, clindamycin) are effective in acne inflammation.
The main limitation in the use of topical antibiotics is the emergence of antibiotic resistance on the part of Propionibacterium acnes.
To avoid development of resistance:
- Avoid concomitant treatment with oral antibiotics
- Not to continue the antibiotic treatment longer than necessary
- Short treatment with antimicrobials (benzoyl peroxide, azelaic acid).
Topical retinoids
The tretinoin, isotretinoin and its isomer, are indicated for the treatment of comedonal acne. Treatment should be continued until no new lesions appear. Topical retinoids should not be used in acne severe, affecting a large body area.
These drugs should be used with caution on sensitive skin, avoiding contact with mucous membranes.
It should also be avoided exposure to UV light (sunlight, sunlamps).
Retinoids are contraindicated in pregnancy.
The most common side effects observed after treatment with topical retinoids are local reactions, such as burning, erythema, abrasions, itching, dryness, peeling. You can see temporary changes in skin pigmentation. The Adapalene is less irritating effects than other topical retinoids.
Oral antibiotics
In the case where the topical treatment is not effective can be taken into account the systemic antibacterial therapy, possibly associated with the use of topical Benzoyl peroxide.
The drugs are elective tetracycline (tetracycline, oxytetracycline, at a dose of 500 mg 2 times a day).
If no improvement is seen after 3 months of therapy, you should switch to another class of antibiotics.
Alternatives to tetracyclines: Doxycycline (100 mg / day) or minocycline (100 mg / day).
Concomitant use of antibiotics for the topical and systemic use is contra-indicated for the possible onset of resistance to antibiotics.
In the case where the topical treatment is not effective can be taken into account the systemic antibacterial therapy, possibly associated with the use of topical Benzoyl peroxide.
The drugs are elective tetracycline (tetracycline, oxytetracycline, at a dose of 500 mg 2 times a day).
If no improvement is seen after 3 months of therapy, you should switch to another class of antibiotics.
Alternatives to tetracyclines: Doxycycline (100 mg / day) or minocycline (100 mg / day).
Concomitant use of antibiotics for the topical and systemic use is contra-indicated for the possible onset of resistance to antibiotics.
Oral hormones
In women who do not respond to antibiotic therapy may be useful to the administration of the combination ethinylestradiol and cyproterone acetate.
The contraindications of hormone therapy include: pregnancy, thrombosis.
Oral retinoids
The Isotretinoin is indicated for the treatment of acne nodular cystic and conglobata, severe acne, scarring, resistant to an adequate course of antibiotic therapy. Moreover, the isotretinoin may be useful, even in women who develop acne in the third and fourth decades.
The main side effects isotretinoin are dry skin and mucosa, epistaxis, and joint pain.
The Isotretinoin is teratogenic. In women of childbearing age should be prescribed the drug associated with contraceptives.
In women who do not respond to antibiotic therapy may be useful to the administration of the combination ethinylestradiol and cyproterone acetate.
The contraindications of hormone therapy include: pregnancy, thrombosis.
Oral retinoids
The Isotretinoin is indicated for the treatment of acne nodular cystic and conglobata, severe acne, scarring, resistant to an adequate course of antibiotic therapy. Moreover, the isotretinoin may be useful, even in women who develop acne in the third and fourth decades.
The main side effects isotretinoin are dry skin and mucosa, epistaxis, and joint pain.
The Isotretinoin is teratogenic. In women of childbearing age should be prescribed the drug associated with contraceptives.
thanks for the advice. i will try it!
ReplyDeletewelcome! and thanks for visiting!
ReplyDelete